The Biochemistry Biotechnology Facility (BBF) offers an automated DNA sequencing service which can be used for sequence of analysis of plasmid, PCR, and large DNA samples. This service utilizes a Perkin Elmer/Applied Biosystems 3100 Genetic Analyzer and Big Dye Terminator chemistry v3.1.
The Laboratory for Computational Molecular Science maintains 2 Silicon Graphics High Resolution Graphics Workstations and offers an array of molecular modeling and quantum mechanical software.
Software available
- MSI QUANTA/CHARM
- Cerius
- Tripos Sybil
- Spartan
- MacroModel
- Mathematica
Hardware available
- Two Dell work stations
- Two Mac work stations
- Two SG work stations
The Department also maintains numerous microcomputer workstations, superminicomputers, and monochrome/color high-resolution printers.
There are about 1,000 additional micros/UNIX workstations available to students at public clusters throughout the university.
Virtually all campus computers are connected by a major fiber optic ethernet backbone with ready access to the World Wide Web. IUPUI is also a core site for the Abilene Internet 2 Project.
The Department of Chemistry and Chemical Biology operates a mass spectrometry (MS) facility to provide top-quality MS support for students and researchers.
We currently specialize in walk-up MS analysis for GC-MS and LC-MS to provide hands-on MS instrumentation training.
Instruments currently available for walk-up use include:
- An Agilent 6890-5973 GC-MS
- An Agilent 7890-5975 GC-FID/GC-MS
- An Agilent 1100-6130A LC-MS with ESI
This facility also contains an Agilent 1200SL-6410 rapid resolution LC-Triple Quad MS with sensitivity upgrade and an Agilent 1200-6520 capillary LC-Q-TOF MS.
These two instruments were obtained through a National Science Foundation grant to support multiple research efforts at IUPUI. While they are not currently available for walk-up use, arrangements can be made for sample analysis by staff, or researcher training for larger projects if instrument time is available.
The facility also contains a SpectrumMill MS proteomics workbench, Bioconfirm, Mass Profiler, Mass profiler Professional, and a METLIN database for data analysis.
The Nanoscale Imaging Center (NIC) completes the existing biomedical imaging capabilities at IUPUI, along with the Indiana Center of Excellence in BioMedical Imaging (IN-CEBI) with its whole body imaging focus, and the Indiana Center for Biological Microscopy with its cellular level imaging focus.
The NIC anchors a campus effort to investigate the behavior of single molecules and nanostructures, with an emphasis on medical, biological, and materials science applications.
NIC focus includes the broad areas of:
- Subcellular imaging Biomimetics for biomaterials and biosensors
- Nanotechnology and development of next generation nanoscale imaging probes and instrumentation