Jing Liu, PhD

Assistant Professor


LD 156D
Personal Website:
Research Areas:
Biological Physics


Imaging and microscope

Computational image informatics

Single molecule biophysics

Nanoscale light-matter interactions. 


  • 2010 – 2015Purdue University
    Ph.D. in Biological Engineering (Advisor: Joseph Irudayaraj)
    Thesis: Quantitative mRNA detection with advanced nonlinear microscopy
  • 2007 – 2010 Chinese Academy of Science, China
    M.S. in Optics (Advisor: Jingsong Wei)
    Thesis: Super resolution nonlinear optical lithography
  • 2003 – 2007 Nanjing University, China
    B.S. in Physics 

Publications & Professional Activity

  1. P. Kumar*, J. Liu*, Y. Hu, A. Bandopadhyay, S. K. Pati, J. Irudayara, and G. J. Cheng, “Graphene/BN heterolayered metamaterials”, Nano Letters, Revision submitted (2018). (*co-first author)
  2. F. Li, A. Chen, Y. Wang, Y. Fan, R. Prakash, B. Li, H. Yokota, and J. Liu, “Vinculin Force Sensor Detects Tumor-Osteocyte Interactions”, Scientific Reports, Revision submitted (2018).
  3. N. S. Moreno, J. Liu, K. M. Haas, L. L. Parker, C. Chakraborty, S. J. Kron, K. Hodges, L. D. Miller, P. J. Robinson, S. A. Lelievre, and P. A. Vidi, “NuMA is a negative regulator of 53BP1 in DNA double-strand break repair”, EMBO Reports, in revision.
  4. P. Kumar, J. Liu, Y. Hu, SRKC Yamijala, X. Wang, S. K. Pati, J. Irudayaraj, and G. Cheng, “Lead Oxide: A New 2D Material with Visible Light Sensitivity”, Small, 14, 1703346 (2018).
  5. Y. Cui, J. Liu, and J. Irudayaraj, “Beyond Quantification: In situ Analysis of Transcriptome and PremRNA Alternative Splicing at the Nanoscale”. WIREs Nanomedicine & Nanobiotechnology, 9, e1443 (2017).
    • Cover article
  6. S. Bogdanov, M. Y. Shalaginov, A. Akimov, A. S. Lagutchev, P. Kapitanova, J. Liu, D. Woods, M. Ferrera, P. Belov, J. Irudayaraj, A. Boltasseva, and V. M. Shalaev, “Electron spin contrast of Purcellenhanced nitrogen-vacancy ensembles in nanodiamonds”. Phys. Rev. B 96, 035146 (2017)
  7. J. Liu, and J. Irudayaraj, “Non-fluorescent quantification of single mRNA with transient absorption microscopy”, Nanoscale, 8, 19242-19248 (2016).
    • Cover article, highlighted in SDSMT news.
  8. Y. Cui, J. Liu, and J. Irudayaraj, “Beyond Quantification: In situ Analysis of Transcriptome and PremRNA Alternative Splicing at the Nanoscale”. WIREs Nanomedicine & Nanobiotechnology, DOI: 10.1002/wnan.1443 (2016).
  9. Y. Cui, X. Wang, W. Ren, J. Liu, and J. Irudayaraj, “Optical Clearing Delivers Ultrasensitive Hyperspectral Dark-Field Imaging for Single-Cell Evaluation”, ACS Nano, 10, 3132-3143 (2016).
  10. J. Liu, I. Cho, N. Damayanti, and J. Irudayaraj, “Single Molecule Detection in Cancer Tissues using Second Harmonic Generation Nanocrystals”, Journal of Biomedical Optics 20, 096016 (2015).
  11. J. Liu, P. Vidi, S. A. Lelièvre, and J. M. K. Irudayaraj, “Nanoscale Histone Localization in Live Cells Reveals Reduced Chromatin Mobility in Response to DNA Damage”, Journal of Cell Science, 128, 599-604 (2015).
  12. J. Liu, P. Kumar, Y. Hu, G. Cheng, and J. Irudayaraj, “Enhanced Multi-photon Emission from CdTe/ZnS Quantum Dots Decorated on Single Layer Graphene”, Journal of Physical Chemistry C, 119, 6331-6336 (2015).
  13. M. Y. Shalaginov, V. V. Vorobyov, J. Liu, M. Ferrera, A. V. Akimov, A. Lagutchev, A. N. Smolyaninov, V. V. Klimov, J. Irudayaraj, A. V. Kildishev, A. Boltasseva, and V. M. Shalaev, “Enhancement of Single-Photon Emission from Nitrogen-Vacancy centers with TiN/(AlSc)N Hyperbolic Metamaterial”. Laser & Photonics Reviews, 9, 120-127 (2015). 
  14. J. Liu, I. Cho, Y. Cui, and J. Irudayaraj, “Second Harmonic Super-resolution Microscopy for Quantification of mRNA at Single Copy Sensitivity”, ACS Nano, 8, 12418-27 (2014).
  15. P. Vidi, J. Liu, S. Jayaraman, G. Dorfman, D. Salles, M.Gray, P. Abad, P. V. Moghe, J. M. K. Irudayaraj, L. Wiesmüller, and S. A. Lelièvre, “NuMA Promotes Homologous Recombination Repair by Regulating the Accumulation of the ISWI ATPase SNF2h at DNA Breaks”, Nucleic Acids Research, 42, 6365-6379 (2014).
  16. G. Naik, B. Saha, J. Liu, S. M. Saber, E. Satach, J. Irudayaraj, T. D. Sands, V. M. Shalaev, and A. Boltasseva, “Epitaxial superlattices with titanium nitride as a plasmonic component for optical hyperbolic metamaterials”. Proceedings of the National Academy of Sciences, 1319446111 (2014).
    • Highlighted in Purdue news room
  17. J. Liu, X. Jiang, S. Iishi, V. Shalaev, and J. Irudayaraj, “Quantifying Local Density of Optical States by Fluorescence Lifetime Imaging”. New Journal of Physics, 16, 063069 (2014).
  18. J. Liu, J. Irudayaraj, “Second Harmonic Generation Correlation Spectroscopy at Single Molecule Level”, Optics Express, Vol. 21, 27063-27073 (2013).
  19. M. Shalaginov, S. Iishi, J. Liu, J. Liu, J. Irudayaraj, A. Lagutchev, A.V. Kindishev, and V. Shalaev, “Broadband enhancement of spontaneous emission from nitrogen-vacancy centers in nanodiamonds by hyperbolic metamaterials”. Applied Physics Letter, 102, 173114 (2013).
  20. J. Wei, J. Liu, and M. Xiao, “Giant Optical Nonlinearity of Silver-doped Silicon Thin Film at Low Power Input: Laser-triggered Cluster Resonance”. Applied Physics A: Materials Science & Processing, 11, 6464-3 (2011).
  21. J. Liu, S. Liu, and J. Wei, “Origin of the Giant Optical Nonlinearity of Sb2Te3 phase change materials”. Applied Physics Letter, 97, 261903 (2010).
  22. J. Wei, and J. Liu, “Direct Observation of Below-Diffraction-Limited Optical Spot induced by Nonlinear Saturable Absorption of Ag-doped Silicon nanofilms”. Optics Letters, 35, 3126-3128, (2010).
  23. J. Liu, and J. Wei, “Optical Nonlinear Absorption Characteristics of AgInSbTe Phase Change Thin Films”. Journal of Applied Physics, 106, 083112, (2009).
  24. J. Wei, J. Liu, and X. Jiao, “Sub-wavelength Direct Laser Writing by Strong Optical Nonlinear Absorption and Melt-ablation Threshold Characteristics”. Applied Physics Letter, 95, 241105, (2009).
  25. K. Chen, G. Li, F. Gao, J. Liu, J. Liu, and J. Zhu, “Conducting Grain Boundaries in the Highdielectric-constant Ceramic CaCu3Ti4O12”. Journal of Applied Physics, 101, 074101, (2007).
  26. K. Chen, S. Yuan, P. Li, F. Gao, J. Liu, G. Li, A. Zhao, X. Lu, J. M. Liu, and J. S. Zhu, “High Permittivity in Zr Doped NiO Ceramics”, Journal of Applied Physics, 102, 034103, (2007).
  27. J. Liu, and J. Wei, “Single Beam Parameter Tunable Z-scan Measurement”. Issued Data: 04/20/2011, China, Issued No.: ZL 2009 1 0054823.1


  • 2015 Outstanding PhD Student, Purdue University
  • 2015 Outstanding Graduate Student for Research Excellence, Purdue University
  • 2014 Bilsland Fellow, Purdue University
  • 2012 SIRG Cancer Center Fellowship, Purdue University 
  • 2011 Ismail Travel Grant, Purdue University
  • 2010 Outstanding Graduate Student, Chinese Academy of Science
  • 2004 - 2006 Excellent Student, Nanjing University