Indiana University Purdue University Indianapolis

Karl Dria Ph.D.

Assistant Research/Instrumentation Scientist, Chemistry


B.S., Ashland University, 1997
M.S., The Ohio State University, 2000
Ph.D., The Ohio State University, 2004
Postdoctoral, Purdue University, 2004-2005

Current Research

My research interests involve using modern analytical instrumentation to better understand natural, environmental, biological and chemical systems. In addition to teaching instrumental analysis and physical chemistry courses, my primary role is to support research. This involves writing proposals for and acquiring new instrumentation, maintaining and supporting the departmental instrumentation, helping users develop new analytical methods, training users to use instrumentation (predominantly NMR, GC-MS, LC-MS and LC-MS-MS), and occasionally analyzing samples for service.

Select Publications

L. Yang, G. Lin, D. Liu, K. Dria, J. Telser, and L. Li “Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates” Jounal of the American Chemical Society 2011, 133, 10434–10447.

A. Goulding, S. Shrestha, K. Dria, E. Hunt and S. Deo “Red fluorescent protein variants with incorporated non-natural amino acid analogues” Protein Engineering Design and Selection2008, 21, 101-106.

S. Duan, T. S. Bianchi, A. Shiller, K. Dria, P. H. Hatcher and K. R. Carmen “Variability in the bulk composition and abundance of dissolved organic matter in the lower Mississippi and Pearl Rivers (USA)” J. Geophys. Res. (Biogeosciences) J. Geophys. Res. 2007, 112 (G2).

S. B. Schwede-Thomas, Y.-P. Chin, K. J. Dria, P. Hatcher, E. Kaiser and B. Sulzberger "Characterizing the properties of dissolved organic matter isolated by XAD and C-18 solid phase extraction and ultrafiltration" Aquatic Sciences 2005, 67, 61-71.

T. S. Bianchi, T. Filley, K. J. Dria and P. Hatcher "Temporal Variability in Sources of Dissolved Organic Carbon in the Lower Mississippi River" Geochimica et Cosmochimica Acta 2004, 68, 959-967.

E. Kaiser, A. J. Simpson, K. J. Dria, B. Sulzberger and P. G. Hatcher "Solid-state and multidimensional solution-state NMR of solid phase extracted and ultrafiltered riverine dissolved organic matter" Environmental Science & Technology 2003, 37, 2929-2935.

K. J. Dria, J. R. Sachleben and P. G. Hatcher "Solid-state carbon-13 nuclear magnetic resonance of humic acids at high magnetic field strengths" Journal of Environmental Quality 2002, 31, 393-401.

P. G. Hatcher, K. J. Dria, S. Kim and S. W. Frazier "Modern analytical studies of humic substances" Soil Science 2001, 166, 770-794.

X. Zang, J. D. H. van Heemst, K. J. Dria and P. G. Hatcher "Encapsulation of protein in humic acid from histosols as an explanation for the occurrence of organic nitrogen in soil and sediment" Organic Geochemistry 2000, 31, 679-695.